Introduction

• JOINSTAR's Cytokine Solution offers both single and multiplex dual-platform detection support, covering 13 core cytokines including IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-17, TNF-α, IFN-α, IFN-γ, and IL-2R.

Clinical Applications

• Cytokines regulate cell growth and differentiation by binding to corresponding receptors, modulating the immune response. They are characterized by pleiotropic, overlapping, synergistic, antagonistic, and networking properties. In scenarios such as sepsis, autoimmune diseases, tumor immunotherapy, and organ transplantation, dynamic cytokine detection helps assess disease severity, guide medication, and determine prognosis. Combined detection enables systematic analysis of pro-inflammatory and anti-inflammatory balance and Th1/Th2 immune drift.
• ICU: Early warning and dynamic monitoring of cytokine storm in sepsis patients.
• Oncology/Hematology: Monitoring of cytokine release syndrome related to immunotherapy (CAR-T, immune checkpoint inhibitors).
• Rheumatology: Disease activity assessment in autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.
• Transplant Department: Immune rejection monitoring after organ transplantation and immunosuppressant regimen adjustment.
• Emergency Department: Rapid differential diagnosis of fever of unknown origin and inflammation status assessment.