I-progesterone(PROG)

Incazelo emfushane:


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izimpawu Zomkhiqizo Ezibalulekile

Ikhithi Igama: Ikhithi yokutholwa kweprogesterone 

Indlela:I-Fluorescence dry quantitative immunoassay

Ibanga lokulinganisa i-assay:0.37ng/mL ~40.00ng/mL

Isikhathi se-incubation:10 imizuzu

Sngokwanele:I-serum yomuntu, i-plasma (EDTA-K2 anticoagulant)50ul, igazi eliphelele (EDTA-K2 anticoagulant)80ul

Ibanga lesithenjwa: 

Ubulili

Isiteji

ububanzi bereferensi

owesifazane

Isigaba se-Follicular

<0.37-1.98ng/mL (5%CI-95%CI)

Isigaba se-Luteal

<0.88-30.43ng/mL (5%CI-95%CI)

Ngemva kokuya esikhathini

<0.37-0.8ng/mL (5%CI-95%CI)

Eukukhulelwa kwesigaba sangaphambi kwesikhathi

<4.7-40ng/mL (10%CI-90%CI)

Isitoreji Nokuzinza:

Isivimbeli Sokuthola sizinzile izinyanga eziyi-12 ku-2°C ~8°C.

Idivayisi Yokuhlola Evaliweisuzinzile izinyanga eziyi-12 ku-4°C30°C.

Isingeniso

Ngokunqunywa kwe-in vitro quantitative kokugxila kwe-progesterone (P) ku-serum yabesifazane/i-plasma/igazi lonke.

Kwabesifazane abanesikhathi esivamile.

I-progesterone igcinwa emazingeni aphansi phakathi nesigaba se-follicular, ngokukhuphuka kokukhiqizwa kwe-hormone ye-luteinising kanye nokukhuphuka okubukhali kwe-progesterone phakathi nesigaba se-luteal ngemva kokuphuma kwe-ovulation, ngakho-ke ingasetshenziswa njengenkomba enokwethenjelwa ye-ovulation yemvelo noma eyenziwe .

Umphumela uholela ekushintsheni esibelethweni futhi ulungiselela i-ovary yokufakelwa kweqanda elivundisiwe. I-progesterone enganele esigabeni se-luteal kucatshangwa ukuthi iyimbangela ye-endometrial dysplasia uma amazinga e-progesterone aphansi ngokungavamile.

Uma ukukhulelwa kungenzeki, i-progesterone yehla ezinsukwini ezine zokugcina zomjikelezo njengoba i-corpus luteum iwohloka. Uma ukukhulelwa kwenzeka, i-corpus luteum igcina i-progesterone ekugxilweni kwamaphakathi ne-luteal kuze kube isonto lesithupha lokukhulelwa. Ngaleso sikhathi, i-placenta iba umthombo we-progesterone uma nje ithatha, futhi amazinga e-progesterone akhuphuka ngokuqhubekayo. Ekuqaleni kokukhulelwa, amazinga aphansi e-progesterone abonisa amathuba aphezulu okukhipha isisu ngaphambi kwesikhathi noma ukukhulelwa kwe-ectopic.

Sengiphetha, ukuhlolwa kwe-progesterone kungasetshenziswa ukuthola ukuphuma kweqanda kwabesifazane nokuhlola isigaba se-luteal, esingasiza ekunqumeni ukuzala .

Ukuvumelana Nemihlahlandlela

I-Society of Obstetricians and Gynecologists yaseCanada, SOGCUmhlahlandlela Wokuzilolonga Womtholampilo: I-Progesterone Yokuvimbela Ukuzala Okuzenzakalelayo Ngaphambi Kokuqalah(2020》

Ekuqaleni kokukhulelwa, ukukhiqizwa kwe-progesterone yi-corpus luteum kubalulekile ekugcinweni kokukhulelwa, i-placenta ithatha lo msebenzi ngamaviki angu-7-9 wokukhulelwa. Ku-trimester yesibili, i-progesterone igcina isimo sokuphumula sesibeletho futhi umsebenzi wayo wehla ngokusebenza lapho uqala ukusikwa, kokubili ekuzalweni ngaphambi kwesikhathi nesikhathi sokuzalwa.

Ngaphezu kwalokho, i-progesterone ivimbela i-apoptosis ye-fetus explants kuzo zombili izimo zokuphendula eziyisisekelo nezivuvukalayo.

Ubufakazi bakamuva bocwaningo lomtholampilo lwe-progesterone ekuvimbeleni i-SPB, futhi bunikeze isiqondiso somtholampilo nezincomo zendlela yokwenza, inani labantu elifanelekile, inani labantu elingafaneleki, umthamo, isikhathi kanye nemiphumela engemihle ye-progesterone ekuvimbeleni i-SPB.

Izicelo Zomtholampilo

Ukuqapha i-ovulation 

Izinga le-progesterone yegazi> 5ng/ml libonisa ukuthi i-ovulation.

Ukuhlolwa komsebenzi we-luteal

Ukuhlolwa komsebenzi we-luteal: Izinga le-progesterone yegazi eliphansi kune-physiological ngesikhathi sesigaba se-luteal libonisa ukungasebenzi kahle kwe-luteal.

Ukuxilongwa kwe-ancillary ye-ectopic pregnancy

Ku-ectopic pregnancy, amazinga e-progesterone egazi aphansi kakhulu, iziguli eziningi zingu-<15ng/ml.

Abanye

Izinsiza ekuxilongeni i-pre-eclampsia, ukubhekwa komsebenzi we-placenta, ukuhlolwa okubikezelwe kokuvundiswa kwe-in vitro-ukudluliswa kombungu, njll.


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