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Serum Amyloid A
KitName:Joinstar Serum Amyloid A Detection Kit
Mokhoa:fluorescence dry quantitative immunoassay
Lethathamo la ho lekanya:5.0mg/L ~ 200.0 mg/L
Nako ea ho incubation:5 mets
Se lekaneng: Serum ea batho, plasma (EDTA le Sodium citrate anticoagulant) le mali a feletseng (EDTA le Sodium citrate anticoagulant)
Reference range: Ka tlase ho 10.0mg/L
Polokelo le Botsitso:
✭Thibelo Buffer e tsitsitse bakeng sa likhoeli tse 12 ho 2°C ~8°C.
✭Tiisitsoeng Test Deviceis e tsitsitseng bakeng sa likhoeli tse 12 ho 4°C～30°C.
• Serum amyloid A e hlahisoa ka har'a sebete 'me e bolokiloe haholo ho pholletsa le mefuta ea liphoofolo. E sebetsa joalo ka protheine ea ho ruruha le ea immunomodulatory, e susumetsang ho ruruha ha cytokine secretion, chemotaxis ea neutrophils le mast cells le ho fetola likarabo tsa 'mele oa ho itšireletsa mafung.
• Ke protheine e hlobaetsang ea chronotropic eo e leng ea sehlopha sa heterogeneous ea lelapa la apolipoprotein mme e teng ka bongata maling a motho ea phetseng hantle.
• Karabelo ea karolo e matla nakong ea ho ruruha, e susumelitsoeng ke IL - 1, IL - 6 le TNF, SAA e ka phahamisetsoa ho 10-1000 linako tse ling tsa bohlokoa bo tloaelehileng.
• SAA e ka lemohuwa nakong ya 3-6 h ya tshwaetso mme ka halofo e kgutshwane-bophelo ba 50 min. E na le kutloelo-bohloko ho feta CRP, 'me motsoako oa matšoao ana a mabeli a ka fana ka phapang e ntle ea ho ruruha le tšoaetso.
• Boemong bo matla ba tšoaetso ea kokoana-hloko, SAA e phahame, hangata ho 10-100 ng/mL. leha ho le joalo, mokhahlelong o hlobaetsang oa tšoaetso ea baktheria, SAA e phahame ka tekanyo e kholo ho feta tšoaetsong ea kokoana-hloko, esita le ho fihla ho 100-1000mg/L.
• Li-biomarker tsa mali tsa pele bakeng sa kotsi ea lisele le ho ruruha
♦ Serum amyloid A (SAA) ke sesupo sa mali sa pele le se hlokolosi bakeng sa kotsi ea lisele le ho ruruha 'me e bontšitsoe mafung a mangata a ho ruruha.
♦ Boemo ba SAA e potolohang maling bo tsejoa hore bo eketseha haholo ka lebaka la tšenyo ea lisele kapa ho ruruha, ho e khetholla e le protheine e matla.
♦ Ho potoloha SAA ho ka 'na ha eketseha ho fihla ho 1000-menahano ka mor'a ho ruruha, tšoaetso, kotsi ea lisele le necrosis ea lisele le ho fokotseha ka potlako ka mor'a ho hlaphoheloa.
• Tlhahlobo e fapaneng ea tšoaetso ea baktheria kapa kokoana-hloko
♦ Boemo ba SAA bo lula bo phahame ho feta 10mg/L empa bo le ka tlase ho 100mg/L, bo fana ka maikutlo a hore tšoaetso ea vaerase e ka etsahala.
♦ Boemo ba SAA bo lula bo phahame ho feta 100mg/L bo bontša boemo bo matla ba tšoaetso ea baktheria.
• Ho beha leihlo tsoelo-pele ea mafu a tšoaetsanoang
SAA e ka sebelisoa e le ntho e ikemetseng ho lekola ho teba ha mafu a baktheria, kokoana-hloko le a mang a tšoaetsanoang le ho ruruha, hangata boemo bo fetang 500 mg/L bo bontša boemo bo tebileng.
• Ho lemoha ha motsoako oa SAA le CRP
Boemo ba SAA bo a phahama mafu a vaerase le a baktheria mme e ameha haholo ho ruruha ho fokolang ho feta CRP. Ka hona, motsoako oa SAA le CRP e ka fa baoki boitsebiso bo eketsehileng.
• Tekolo ea prognostic ea ho ruruha
Maemo a SAA a fokotseha ka potlako ka mor'a qeto ea ho ruruha, e leng se etsang hore tekanyo ea SAA e be sesebelisoa se molemo sa ho lekola tsela ea ho ruruha ho motho ka mong.
