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β2-Microglobulin (β2-MG)
Kit Lebitso: β2-Microglobulin Detection Kit
Mokhoa:Fluorescence dry quantitative immunoassay
Lethathamo la ho lekanya:
✭Plasma le Serum: 0.40mg/L~20.00mg/L
✭Moroto: 0.15mg/L~8.00mg/L
Nako ea ho incubation:Metsotso e 10
Se lekaneng: Serum ea batho, plasma (EDTA anticoagulant), moroto
Reference range:
✭ Plasma le Serum: 1.00mg/L~3.00mg/L
✭Moroto≤0.30mg/L
Polokelo le Botsitso:
✭Sesiba sa ho hlwaya se tsitsitse bakeng sa likhoeli tse 12 ho 2°~8°C.
✭Sesebelisoa se Tiisitsoeng sa Teko se tsitsitse likhoeli tse 12 ho 2°C～30°C.
•β2-microglobulin (β2-MG) ke globulin e nyenyane ea molek'hule e hlahisoang ke lymphocyte, platelets le polymorphonuclear leukocyte e nang le boima ba molek'hule ea 11,800.
•Ke ketane ea β (ketane e khanyang) ea human lymphocyte antigen (HLA) e holim'a sele. . E fumaneha haholo maemong a tlase haholo ho plasma, moroto, cerebrospinal fluid, mathe.
•Ho batho ba phetseng hantle, sekhahla sa motsoako le palo ea tokollo ea β2-MG ho tsoa ho membrane ea sele e lula e le teng. β2-MG e ka tlhotluoa ka bolokolohi ho glomeruli, 'me 99.9% ea β2-MG e tlhotliloeng e khutlisetsoa hape e senyeha ke li-proximal renal tubules.
•Maemong ao ts'ebetso ea glomerulus kapa renal tubule e fetotsoeng, boemo ba β2-MG maling kapa moroto le bona bo tla fetoha.
•Boemo ba β2-MG ka serum bo ka bonahatsa ts'ebetso ea ho hloekisa ea glomerulus 'me kahoo boemo ba β2-MG moroto ke letšoao bakeng sa tlhahlobo ea tšenyo ea li-proximal tubules tsa renal.
•《KDIGO Clinical Practice Guideline on Glomerular Diseases (2020)》
Tekanyo ea ho tsoa ha moroto ho IgG, β-2 microglobulin, protheine e tlamang retinol, kapa α-1 macroglobulin e kanna ea ba le ts'ebeliso ea bongaka le ea pele ho mafu a itseng, joalo ka Membranous nephropathy le Focal segmental glomerulosclerosis.
•《KDIGO Clinical Practice Guideline for Acute Kidney Injury (2012)》
Ntlha ea pele, ho sa tsotellehe hore na kotsi e mpe ea liphio (AKI) e hlahile, lithuto tsohle li ne li e-na le bopaki ba pele ba ho se sebetse ha li-tubula le khatello ea kelello, e bontšitsoeng ke β2-microglobulinuria ea pele.
•Tekanyetso ea ts'ebetso ea filthara ea glomerular
Lebaka le ka sehloohong la keketseho ea β2-MG maling le β2-MG e tloaelehileng morotong e ka 'na ea e-ba ho fokotseha ha tšebetso ea glomerular filtration, eo hangata e leng ho nephritis e matla le e sa foleng le ho hloleha ha renal, joalo-joalo.
•Tekolo ea renal tubular reabsorption
Boemo ba β2-MG maling bo tloaelehile, empa ho eketseha ha moroto ho bakoa haholo ke ts'ebetso e hlakileng ea renal tubular reabsorption, e fumanoang ts'ebetsong ea congenital proximal renal tubules, Fanconi syndrome, chefo e sa foleng ea cadmium, lefu la Wilson, ho hana ho fetisoa ha renal, etc.
• Mafu a mang
Maemo a phahameng a β2-MG a ka boela a bonoa meferong e amang lisele tse tšoeu tsa mali, empa e bohlokoa haholo ho batho ba sa tsoa fumanoa ba e-na le myeloma e mengata.
