Serum Amyloid A

Tsanangudzo Pfupi


Product Detail

Product Tags

Key Product Characters

KitName:Joinstar Serum Amyloid A Detection Kit

Nzira:fluorescence yakaoma quantitative immunoassay

Chiyero chekuyera chiyero:5.0mg/L ~ 200.0 mg/L

Incubation nguva:5min

Szvakakwana:Serum yevanhu, plasma (EDTA uye Sodium citrate anticoagulant) uye ropa rose (EDTA uye Sodium citrate anticoagulant)

Reference range:<10.0mg/L

Kuchengetedza uye Kugadzikana:

Detection Buffer yakagadzikana kwemwedzi gumi nemiviri pa2°C ~8°C.

Yakavharwa Test Deviceisyakagadzikana kwemwedzi gumi nemiviri pa4°C30°C.

Nhanganyaya

Serum amyloid A inogadzirwa muchiropa uye inochengetedzwa zvakanyanya mumarudzi ese. Inoshanda seprotein inoputika uye inodzivirira muviri, inokonzera kuputika kwe cytokine secretion, chemotaxis yeutrophils uye mast masero uye inogadzirisa mhinduro dzekudzivirira zvirwere.

Iyo acute chronotropic protein inova yeheterogeneous kirasi yemhuri yeapolipoprotein uye iripo muhuwandu hwekutevera muropa remunhu ane hutano.

Muchikamu chekupindura panguva yekuzvimba, inokurudzirwa neIL-1, IL-6 uye TNF, SAA inogona kukwidziridzwa kusvika ku10-1000 nguva yakajairika kukosha.

SAA inoonekwa mukati me3-6 h yehutachiona uye nehupfupi hafu yehupenyu hwe50 min. Inonyanya kunzwisiswa kupfuura CRP, uye kusanganiswa kweaya mamakisi maviri anogona kupa musiyano uri nani wekuzvimba uye hutachiona.

Muchikamu chakaoma chehutachiona hwehutachiona, SAA inokwidziridzwa, kazhinji kusvika 10-100 ng/mL. zvisinei, muchikamu chakaoma chehutachiona hwehutachiona, SAA inokwidziridzwa kusvika pamwero mukuru kudarika muhutachiona hwehutachiona, kunyange kusvika ku100-1000mg / L.

Clinical Applications

 Kutanga kweropa biomarker yekukuvara kwetishu uye kuzvimba

♦ Serum amyloid A (SAA) inokurumidza uye inonzwisisika yeropa biomarker yekukuvara kwetishu uye kuzvimba uye yakaratidzwa muzvirwere zvakawanda zvinopisa.

♦ Kufamba kweSAA muropa kunozivikanwa kuti kunowedzera zvakanyanya maererano nekukuvadzwa kwetishu kana kuzvimba, zvichiratidza seprotein yechikamu cheacute.

♦ Kutenderera SAA kuisa pfungwa kunogona kuwedzera kusvika ku1000-kutevera kuzvimba, utachiona, kukuvara kwetishu uye cell necrosis uye kuderera nokukurumidza mushure mekupora.

Kuongororwa kwakasiyana kwehutachiona kana hutachiona hwehutachiona

♦ Chiyero cheSAA chinoramba chiri pamusoro pe10mg/L asi yakaderera pane 100mg/L, zvinoratidza kuti utachiona hwehutachiona hunonyanya kuitika.

♦ Chiyero cheSAA chinoramba chiri pamusoro pe100mg/L chinoratidza zvakanyanya chikamu chechirwere chebhakitiriya.

 Kuongorora kufambira mberi kwezvirwere zvinotapukira

SAA inogona kushandiswa sechinhu chakazvimirira chekuongorora kuomarara kwebhakitiriya, hutachiona uye zvimwe zvirwere zvinotapukira uye kuzvimba, kazhinji nhanho yakakura kupfuura 500 mg/L inoratidza mamiriro akakomba.

 Musanganiswa wekuonekwa kweSAA neCRP

Chiyero cheSAA chinokwidziridza muzvese utachiona neutachiona uye inonyatsa kunzwa kuzvimba zvishoma pane CRP. Naizvozvo,  musanganiswa weSAA neCRP unogona kupa varapi mamwe mashoko.

 Prognostic kuongororwa kwekuzvimba

Concentrations yeSAA inokurumidza kudzikira mushure mekugadziriswa kwekuzvimba, zvichiita kuti SAA kuyerwa kuve chishandiso chinobatsira chekutarisa mafambiro ekuzvimba mumunhu.


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