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Chichewa

Progesterone (PROG)

Kufotokozera Kwachidule:


Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Makhalidwe Ofunika Kwambiri

Zida Dzina: Progesterone Detection kit 

Njira:Fluorescence dry quantitative immunoassay

Mlingo woyezera:0.37ng/mL ~ 40.00ng/mL

Nthawi ya incubation:10 mphindi

Szokwanira: Seramu yamunthu, plasma (EDTA-K2 anticoagulant)50ul, magazi athunthu (EDTA-K2 anticoagulant)80ul

Masanjidwe ake: 

Jenda

Gawo

osiyanasiyana

wamkazi

Gawo la follicular

<0.37 - 1.98ng/mL (5%CI-95%CI)

Gawo la Luteal

<0.88-30.43ng/mL (5%CI-95%CI)

Post-osiya kusamba

<0.37-0.8ng/mL (5%CI-95%CI)

Emimba yoyambirira

<4.7 -＞40ng/mL (10% CI-90% CI)

Kusunga ndi Kukhazikika: 

✭Chotchinga Chotchinga chimakhala chokhazikika kwa miyezi 12 pa 2°C ~8°C. 

✭Chosindikizira Mayeso Chipangizois chokhazikika kwa miyezi 12 pa 4°C～30°C.

Mawu Oyamba

•Kutsimikiza kwa in vitro kuchuluka kwa progesterone (P) mu seramu yachikazi/plasma/magazi athunthu.

•Mu akazi yachibadwa kusamba.

•Progesterone imasungidwa pamiyeso yotsika panthawi ya follicular, ndi kuwonjezeka kwa kupanga kwa mahomoni a luteinising komanso kukwera kwakukulu kwa progesterone panthawi ya luteal pambuyo pa ovulation, choncho ingagwiritsidwe ntchito ngati chizindikiro chodalirika cha kutulutsa kwachilengedwe kapena kuchititsa kuti dzira .

•Zotsatira zake zimabweretsa kusintha kwa chiberekero ndikukonzekeretsa ovary kuti dzira la umuna likhale lopangidwa. Kusakwanira kwa progesterone mu gawo la luteal kumaganiziridwa kuti ndi chifukwa cha endometrial dysplasia ngati progesterone yotsika kwambiri imachitika.

•Ngati kutenga pakati sikuchitika, progesterone imatsika m'masiku anayi otsiriza a corpus luteum pamene corpus luteum imachepa. Ngati kutenga pakati, corpus luteum imasunga progesterone pakati pa nthawi ya luteal mpaka sabata lachisanu ndi chimodzi la bere. Panthawi imeneyi, chiberekero chimakhala gwero la progesterone kwa nthawi yayitali, ndipo progesterone imakwera mosalekeza. Kumayambiriro kwa mimba, kuchepa kwa progesterone kumawonetsa mwayi waukulu wochotsa mimba asanakwane kapena ectopic pregnancy.

•Pomaliza, kuyezetsa kwa progesterone kungagwiritsidwe ntchito kuti azindikire kutulutsa kwa ovulation mwa amayi ndikuwunika gawo la luteal, lomwe lingathandize kudziwa kubereka.

Kugwirizana & Malangizo

•Bungwe la Obstetricians ndi Gynecologists ku Canada, SOGC《Malangizo Othandizira Pachipatala: Progesterone for Prevention of Spotaneous Preterm Birth(2020》

Kumayambiriro kwa mimba, kupanga progesterone ndi corpus luteum ndikofunikira kuti pakhale mimba, ndi placenta ikugwira ntchitoyi ndi 7 - 9 milungu yoyembekezera. Mu trimester yachiwiri, progesterone imasunga mpumulo wa chiberekero ndipo ntchito yake imachepa mpaka kumayambiriro kwa nthawi yobereka, ponse pa nthawi yobereka komanso yobereka.

Kuphatikiza apo, progesterone imalepheretsa apoptosis ya fetal membrane explants muzochitika zonse zoyambira komanso zotupa.

Umboni waposachedwa wa kafukufuku wachipatala wa progesterone popewa SPB, komanso anapereka malangizo achipatala ndi malangizo a kachitidwe, chiwerengero choyenera, chiwerengero chosayenera, mlingo, nthawi ndi zotsatira za progesterone popewa SPB.

Ntchito Zachipatala

•Kuwunika kwa ovulation 

Miyezo ya progesterone m'magazi> 5ng/ml imasonyeza kuti ovulation.

•Kuwunika kwa ntchito ya luteal

Kuwunika kwa ntchito ya luteal: Kutsika kwa progesterone m'magazi a thupi panthawi ya luteal kumasonyeza kusakwanira kwa luteal.

•Kuzindikira kothandizira kwa ectopic pregnancy

Mu ectopic pregnancy, ma progesterone a m’magazi amatsika kwambiri, odwala ambiri ochepera 15ng/ml.

•Ena

Thandizo pozindikira za pre-eclampsia, kuyang'ana momwe placenta imagwirira ntchito, kuwunika kwamtsogolo kwa feteleza wa in vitro-kusamutsa mwana wosabadwayo, ndi zina zambiri.

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