Ngwaahịa na-ekpo ọkụ
Igbo

Serum Amyloid A

Nkọwa dị mkpirikpi:


Nkọwa ngwaahịa

Mkpado ngwaahịa

Njirimara ngwaahịa igodo

KitName:Joinstar Serum Amyloid Ngwa nchọpụta

Usoro:fluorescence akọrọ quantitative immunoassay

Oke nlele nyocha:5.0mg/L ~ 200.0 mg/l

Oge nnabata:5min

Szuru oke: Ọbara mmadụ, plasma (EDTA na sodium citrate anticoagulant) na ọbara dum (EDTA na sodium citrate anticoagulant)

Oke ntụaka: <10.0mg/L

Nchekwa na kwụsie ike: 

✭Ihe nchekwa nchọpụta kwụsiri ike maka ọnwa 12 na 2°C ~ 8°C. 

✭Ngwa ule emechiri emechiis kwụsiri ike maka ọnwa 12 na 4 Celsius～30°C.

Okwu mmalite

• A na-emepụta serum amyloid A n'ime imeju ma na-echekwa ya nke ọma n'ofe ụdị. Ọ na-arụ ọrụ dị ka protein na-egbuke egbuke na immunomodulatory, na-eme ka nzuzo cytokine na-egbuke egbuke, chemotaxis nke neutrophils na sel mast ma na-emezi nzaghachi mgbochi.

• Ọ bụ nnukwu protein chronotropic nke sitere na klaasị dị iche iche nke ezinụlọ apolipoprotein ma dị na ọnụọgụ n'ọbara mmadụ nwere ahụike.

• N'ime mmeghachi omume dị ukwuu n'oge mbufụt, nke IL - 1, IL - 6 na TNF kpaliri, SAA nwere ike ibuli elu na 10-1000 ugboro uru nkịtị.

• A na-achọpụta SAA n'ime awa 3-6 nke ọrịa yana yana obere ọkara - ndụ nke 50 min. Ọ dị nro karịa CRP, na nchikota nke akara abụọ a nwere ike inye ọdịiche dị mma nke mbufụt na ọrịa.

• N'oge nnukwu ọrịa nje, SAA na-ebuli elu, na-abụkarị 10-100 ng/mL. Otú ọ dị, na nnukwu oge nke ọrịa nje, SAA na-ebuli elu karịa na nje virus, ọbụna ruo 100-1000mg/L.

Ngwa ụlọ ọgwụ

• Biomarker ọbara mmalite maka mmerụ anụ ahụ na mbufụt

♦ Serum amyloid A (SAA) bụ ihe nrịbama ọbara nke mbụ na nke nwere mmetụta maka mmerụ ahụ na mbufụt ma gosi ya n'ọtụtụ ọrịa mkpali.

♦ Amaara ọkwa SAA na-ekesa n'ọbara ka ọ na-abawanye nke ukwuu na nzaghachi maka mmebi anụ ahụ ma ọ bụ mbufụt, na-ekewa ya dị ka protein na-agba agba.

♦ Ntụgharị uche SAA na-ekesa nwere ike ịbawanye ruo 1000-mpịakọta na-eso mbufụt, ọrịa, mmerụ ahụ anụ ahụ na necrosis cell ma daa ngwa ngwa mgbe mgbake gasịrị.

• Nchọpụta dị iche iche nke ọrịa nje ma ọ bụ nje

♦ Ọkwa SAA na-adị elu karịa 10mg/L mana ọ dị ala karịa 100mg/L, na-egosi na ọ nwere ike ibute ọrịa nje.

♦ Ọkwa SAA na-arị elu karịa 100mg/L nke ukwuu na-egosi nnukwu akụkụ nke ọrịa nje.

• Na-enyocha ọganihu nke ọrịa na-efe efe

Enwere ike iji SAA dị ka ihe nwere onwe ya iji chọpụta oke nje, nje na ọrịa ndị ọzọ na-efe efe na mbufụt, na-abụkarị ọkwa karịrị 500 mg / L na-egosi ọnọdụ dị njọ.

• Nchọpụta ngwakọta nke SAA na CRP

Ọkwa SAA na-ebuli na nje virus na nje nje yana na-enwe mmetụta nke mkpali mkpali dị nro karịa CRP. Ya mere, nchikota  SAA na CRP nwere ike inye ndị dọkịta ozi ndị ọzọ.

• Prognostic nwale nke mbufụt

Ntinye uche nke SAA na-agbada ngwa ngwa mgbe mkpebi nke mbufụt gasịrị, na-eme nha SAA ka ọ bụrụ ngwaọrụ bara uru maka nyochaa usoro mbufụt n'ime mmadụ.

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