Tus nqi tsim nyog Yuav Rapid Antigen Test Kit Rau Covid 19 - Anti-Mullerian Hormone (AMH) - Joinstar

Kit Lub npe: Anti-Mullerian Hormone Detection Kit 

Txoj kev:Fluorescence qhuav quantitative immunoassay

Kev ntsuas ntsuas ntau:0.050ng/mL ~ 25.000ng/mL

Lub sijhawm incubation:15 feeb

Stxaus: Tib neeg cov ntshav, ntshav (EDTA - K2 anticoagulant) thiab tag nrho cov ntshav (EDTA - K2 anticoagulant)

Kev siv ntau yam: 

Cia thiab Stability: 

✭Kev kuaj pom tsis pom kev ruaj khov rau 12 lub hlis ntawm 2 ° C ~ 8 ° C. 

✭Cov cuab yeej kaw kaw ruaj khov rau 12 lub hlis ntawm 4 ° C ~ 30 ° C.

•Anti-Mullerian hormone (AMH) yog glycoprotein, ib qho dimer uas muaj ob qhov sib npaug 72 kDa monomers txuas los ntawm daim ntawv cog lus disulfide. Nws yog tus hloov pauv kev loj hlob zoo-β tsev neeg.

•AMH yog qhov sib txawv ntawm qhov sib txawv ntawm cov txiv neej thiab poj niam txoj kev loj hlob thiab kev loj hlob, thiab muaj qhov sib txawv ntawm nws txoj haujlwm lom neeg.

•Thaum lub sij hawm embryonic txoj kev loj hlob, AMH tswj kev sib txawv thiab kev loj hlob ntawm cov ducts thiab yog qhov tseem ceeb rau kev sib deev sib txawv. Tom qab yug me nyuam, AMH tswj kev ua haujlwm ntawm cov txiv neej testicular mesenchymal hlwb.

•Hauv cov poj niam laus, AMH inhibits kev nrhiav neeg ua ntej ntawm cov hauv paus hniav thiab kev loj hlob ntawm antral follicles, tiv thaiv follicular depletion ntxov ntxov.

•AMH qhia txog lub hnub nyoog - cuam tshuam txog kev poob qis hauv zes qe menyuam ntxov dua li follicle stimulating hormone (FSH), estradiol (E2), inhibin B (inhB) thiab antral follicle suav (AFC), thiab nws qib tsis cuam tshuam los ntawm kev coj khaub ncaws, tshuaj tiv thaiv hormonal. , los yog cev xeeb tub.

•Pawg Neeg Ua Haujlwm ntawm American Society for Reproductive Medicine《Kev tiv thaiv thiab kev kho mob ntawm qhov nruab nrab thiab hnyav ntawm zes qe menyuam hyperstimulation syndrome: cov lus qhia(2016)》

Muaj cov pov thawj ncaj ncees (theem II - 2) tias PCOS, nce AMH qhov tseem ceeb, qib siab estradiol, kev loj hlob ntau, thiab ntau cov oocytes retrieved yog txuam nrog kev pheej hmoo ntawm zes qe menyuam hyperstimulation syndrome (OHSS). (Qib B)

•American College of Obstetricians thiab Gynecologists (ACOG)《Committee kev xav No. 618: Ovarian reserve testing (2015) 》 

Rau cov kws kho mob hauv obstetrician-gynecologists, qhov kev kuaj xyuas zes qe menyuam tsim nyog tshaj plaws los siv hauv kev xyaum yog basal FSH plus estradiol qib lossis AMH qib.

•Pawg Neeg Ua Haujlwm ntawm American Society for Reproductive Medicine《Kev ntsuam xyuas thiab txhais kev ntsuas ntawm zes qe menyuam cia: ib pawg neeg xav(2015)》

Zuag qhia tag nrho, FSH yog qhov kev ntsuam xyuas feem ntau siv rau kev txo qis qis ntawm zes qe menyuam (DOR), tab sis AFC thiab AMH pom muaj qhov sib txawv tsawg dua thiab yog li ntawd yog qhov kev cia siab rau kev kwv yees.

•National Institute for Health and Care Excellence (NICE) 《Fertility problems: kev ntsuam xyuas thiab kev kho mob Clinical guideline (2013)》

Anti-Mullerian cov tshuaj hormones tsawg dua los yog sib npaug rau 5.4 pmol / l rau cov lus teb qis thiab ntau dua lossis sib npaug rau 25.0 pmol / l rau cov lus teb siab.

•《ESHRE kev pom zoo ntawm lub ntsiab lus ntawm 'tsis zoo teb' rau zes qe menyuam stimulation rau hauv vitro fertilization: cov txheej txheem Bologna (2011) 》

Ntau qhov kev tshuaj xyuas tau txheeb xyuas qhov kev kwv yees tus nqi ntawm ib qho thiab kev sim ua ke ua tiav hauv cov xwm txheej basal. Ntawm tag nrho cov kev xeem, AFC thiab AMH muaj qhov zoo tshaj plaws rhiab heev thiab tshwj xeeb rau kev kwv yees cov lus teb ntawm zes qe menyuam.

•Kev soj ntsuam ntawm zes qe menyuam reserve function 

AMH yog ib qho tseem ceeb thiab cov cim tshwj xeeb rau kev ntsuas kev ua haujlwm ntawm zes qe menyuam.

•Kev kuaj mob ntawm lub zes qe menyuam ntxov ntxov (POF)

Qib ntawm AMH raug txo qis hauv cov neeg mob hypoovarianism, thiab nws yuav luag tsis paub meej hauv cov neeg mob POF.

•DKev kuaj mob ntawm polycystic zes qe menyuam syndrome (PCOS)

Qib ntawm AMH hauv cov neeg mob nrog PCOS yog 2-3 zaug siab dua li qub.

•Diagnosis thiab saib xyuas of ovarian granulosa cell qog (GCT)

Nws tau nce siab hauv cov neeg mob nrog GCT thiab siv rau kev ua raws li kev saib xyuas ntawm GCT kev kho mob.

•Prediction ntawm zes qe menyuam teb nyob rau hauv aua ssis reproductive tKev kawm txuj ci (ART)

Nws tuaj yeem siv los kwv yees lub zes qe menyuam lub cev ua haujlwm thiab zes qe menyuam hyperstimulation los tsim cov txheej txheem kev txhawb nqa tus kheej rau kev txhim kho tus menyuam cev xeeb tub rau qee qhov thiab tiv thaiv cov teeb meem.

Figure ua 1. AMH yog secreted los ntawm pre-antral thiab antral follicles.